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“I had a private practice physically very close to California Polytechnic State University in San Luis Obispo,” recalls Dr. Dorman, “and was conducting a number of research projects in conjunction with the university. This particular branch requires that pre-med students complete a research project, and I was already guiding a number of groups of students in research on spinal and orthopedic medical issues. I was approached by students who wanted to do a study on nutrition, which coincided with my increasing interest in Garum.”

Dr. Dorman and researchers at California Polytechnic State University carried out a crossover, double-blind study on Garum that was published in 1995 in The Journal of Advancement in Medicine. The study looked at fifty four college students between the ages of 18 and 25 on the assumption that they are an excellent test group because of the anxiety associated with academic stress. Anxiety levels were measured by the Speilberger State Trait Anxiety Inventory (STAI) test, and then the college students were randomly divided into two groups. Group one received three weeks of Garum followed by three weeks of placebo. Group two received three weeks of placebo followed by three weeks of Garum. Each three week treatment period was followed by a week long washout. Garum markedly reduced anxiety. However, as Dr. Dorman notes: “Garum works slowly, you build up to an effective level in about three weeks, and it takes several weeks to wash out. We learned that from our study. Our washout period was not long enough, so that the group who received Garum first continued to have lower anxiety even on the placebo, because of a slowly declining, residual effect of Garum.”


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